Research Analyst I – Formulations

Job title: Research Analyst I – Formulations

Company: Charles River Laboratories

Job description: For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.Job SummaryCharles River Laboratories (CRL) is seeking a research analyst to join our integrated toxicology (ITox) team at the Kansas City site. This site is the first of its kind, bridging CRL’s Discovery and Safety Assessment business units, while bringing automation to standard lead optimization toxicology study models to deliver rapid study results to our clients. When you join our team, you will have a significant impact on the health and well-being of people across the globe. As a Research Analyst, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.From test article receipt to disposition, the Formulations team works with internal customers and clients providing logistical resources to produce reproducible formulations, investigating/troubleshooting where necessary to achieve a time-oriented, quality formulation bound by protocol and standard operating procedure requirements. The research analyst is proficient in the setup and execution of formulations, under supervision and learning to perform skills independently. Additionally, the research analyst will work towards supporting the site through cross training and working cross functionally as workload allows outside of the lab.ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Calculate required vehicle and test article amounts based on study criteria for preparations.
• Work towards independently generating, verifying, and/or reviewing instructions, and other study data as needed, based on body weights, days of dosing, etc.
• Ability to follow detailed protocols and other reference materials to generate instructions for preparation and sampling of formulated test materials.
• Apply laboratory experience to participate in troubleshooting.
• Demonstrates effective communication skills through formal discussions.
• Actively participate in laboratory development and process improvement initiatives.
• Recognize Formulation and/or data issues and communicate those issues to the Study Director and Management.
• Verify and/or review shipments and formulation procedures to ensure quality and completeness.
• Identify potential scientific issues and develop solutions.
• Execution of formulation instructions and preparation procedures.
• Effectively direct junior technical staff in the execution of formulation instructions and preparation procedures.
• Assist to sterilize laboratory equipment using autoclave or other methods
• Assist in washing and maintenance of glassware and lab cleanliness
• Consult with Sponsor representatives and Principal Investigators/Study Directors on appropriate formulation methods for assigned compounds.
• Participate in scientific discussions with internal and external customers.
• Participate in laboratory investigations, providing scientific input and direction, as needed.
• Participate in the development of procedures for formulation of test articles and compounds in vehicle components for dosing.
• Be responsible for the disposal and transport of residual dosing material, non-regulated pharmaceutical solids, accumulated single-use containers to designated waste receiving areas
• Demonstrate effective communication skills through informal discussions with peers, management, and team
• Cross functionally train and execute on learned/honed skills outside of the Formulations Lab to support the overall pulse of the workload as we embrace a one team culture.
• Performs all other related duties as assigned.

Job QualificationsEducation:

• Bachelor’s degree (B.A./B.S.), or equivalent, in a scientific related discipline.

Experience:

• One year in a relevant field, preferably a pharmaceutical, chemistry, or contract research laboratory.
• An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.
• Certification/Licensure: None.
• Excellent written and verbal communication skills.
• Ability to manage multiple tasks and priorities to achieve goals.
• Computer skills (e.g., Microsoft Office Suite), commensurate with essential functions, including the ability to learn a validated system.
• Ability to ensure that a safe working environment is maintained by observing all safety procedures and working methods by making proper use of protective clothing and equipment, and by reading, understanding, and following all safety documents issued or notified of.
• Ability to ensure the integrity of the studies and fulfill the requirements by performing the activities according to the Business Operating Procedures (BOP) and the Institutional Animal Care and Use Committee (IACUC) rules.
• Ability to work extended hours beyond normal work schedule to include, but not limited to evenings, weekends, extended shifts, and/or extra shifts, sometimes on short notice.
• Ability to work under specific time constraints.

PHYSICAL DEMANDS:

• Must be able to lift, move, manipulate and/or hold heavy objects up to and including 50 pounds; this includes work materials, equipment, and/or supplies.
• Must be able to perform procedures, standing or sitting, for long periods of time, using appropriate instruments, reaching with hands and arms, working in narrow spaces, and wearing safety equipment (PPE) according to OSHA regulations and company standards.
• Must be able to frequently hold and manipulate work materials while utilizing fine motor skills.
• Must be able to regularly provide information to and receive information from/through various technologies, media, sources, and contacts. Must be able to accurately exchange information in these situations.
• Regularly operates a computer and other office productivity machinery, such as a calculator, copy machine, and computer printer.
• Move about inside the work area to access file cabinets, office machinery, etc.
• Specific vision abilities required by this job include close vision, color vision, depth perception, and the ability to adjust focus.

WORK ENVIRONMENT:

• General office and lab working conditions, the noise level in the work environment is usually moderate.
• While performing the duties of this job the employee is regularly required to wear protective clothing (i.e., goggles, face shield, cap, gloves, scrubs, shoe covers), work near toxic or caustic chemicals, work with biohazards.
• The employee may occasionally be exposed to live animals with risk of exposure to allergens, zoonotic disease, and biohazards.
• The employee may occasionally be exposed to fumes or airborne particles, unpleasant odors, and extreme temperature conditions.
• The noise level in the work environment ranges from moderate to high depending upon the task being performed.

The pay rate for this role is $23.50/hour.About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.Equal Employment OpportunityCharles River Laboratories is an Equal Opportunity Employer – all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.For more information, please visit www.criver.com.

Expected salary: $23.5 per hour

Location: Stilwell, KS

Job date: Fri, 07 Mar 2025 23:03:06 GMT

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